Search results for "Chrysopogon aciculatus"

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Analgesic Activity, Chemical Profiling and Computational Study on Chrysopogon aciculatus

2018

Present study was undertaken to evaluate the analgesic activity of the ethanol extract of Chrysopogon aciculatus. In addition to bioassays in mice, chemical profiling was done by LC-MS and GC-MS to identify phytochemicals, which were further docked on the catalytic site of COX-2 enzymes with a view to suggest the possible role of such phytoconstituents in the observed analgesic activity. Analgesic activity of C. aciculatus was evaluated by acetic acid induced writhing reflex method and hot plate technique. Phytochemical profiling was conducted using liquid chromatography mass spectrometry (LC-MS) and gas chromatography mass spectrometry (GC-MS). In docking studies, homology model of human C…

0301 basic medicineRMliquid chromatography mass spectrometrygas chromatography mass spectrometryChrysopogon aciculatushot plate test03 medical and health sciencesAcetic acidchemistry.chemical_compound0302 clinical medicineLiquid chromatography–mass spectrometryPharmacology (medical)Hot plate testPharmacologyChromatographybiologyChrysopogon aciculatuspoaceaelcsh:RM1-950analgesicbiology.organism_classification030104 developmental biologylcsh:Therapeutics. PharmacologychemistryPhytochemicalDocking (molecular)030220 oncology & carcinogenesisTricinGas chromatography–mass spectrometryFrontiers in Pharmacology

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